NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently orien...
SCIENCE
April 13, 2026
De novo formation of cis -regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion
NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently oriented CTCF sites, forming structural loops.
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NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently oriented CTCF sites, forming structural loops.
Author: Nature
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